Number serious, though first ignored (6)
I believe the answer is:
eighty
'number' is the definition.
(eighty is a kind of whole number)
I can't explain the remainder of the clue.
Can you help me to learn more?
(Other definitions for eighty that I've seen before include "22 [FOUR] scores" , "Cardinal" , "4 score" , "Figure" , "Around the World in - Days (Verne)" .)