Nurse interfered with tree pruner -- risk-taker (12)
I believe the answer is:
entrepreneur
'risk-taker' is the definition.
I can't judge whether this defines the answer.
'nurse interfered with tree pruner' is the wordplay.
'nurse' becomes 'EN' (abbreviation for state-enrolled nurse).
'interfered with' indicates anagramming the letters.
'tree'+'pruner'='treepruner'
'treepruner' with letters rearranged gives 'trepreneur'.
'en'+'trepreneur'='ENTREPRENEUR'
Can you help me to learn more?
(Other definitions for entrepreneur that I've seen before include "Businessman who takes more than average risk" , "Business speculator" , "Commercial figure" , "business figure" , "Chap running business" .)