Object of loathing (8)
I believe the answer is:
anathema
'object of loathing' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for anathema that I've seen before include "hated person" , "target of hate" , "Detested person or thing - excommunication" , "denunciation" , "Formal curse leading to excommunication" .)