Obligation on American (4)
I believe the answer is:
onus
'obligation' is the definition.
(thesaurus)
'on american' is the wordplay.
'american' becomes 'us'.
'on'+'us'='ONUS'
(Other definitions for onus that I've seen before include "'Responsibility, task or burden (4)'" , "Responsibilty" , "Weight of responsibility" , "Obligation - charge" , "Burden, duty" .)