Obstructive, with a yen to be different (2,3,3)
I believe the answer is:
in the way
'obstructive' is the definition.
(thesaurus)
'with a yen to be different' is the wordplay.
'to be different' indicates an anagram (I've seen 'is different' mean this).
'with'+'a'+'yen'='withayen'
'withayen' is an anagram of 'IN THE WAY'.
(Other definitions for in the way that I've seen before include "causing a blockage" , "Causing obstruction" , "Obstructing" , "Being . . . . . . . . like 11 Across" , "Impeding one's progress" .)