Octogenarians resisting strong treatment in this region (7)
I believe the answer is:
oceania
'this region' is the definition.
(region of Earth)
I can't explain the rest of the clue.
Can you help me to learn more?
(Other definitions for oceania that I've seen before include "Islands of the central and South Pacific" , "Islands of Pacific and adjacent seas" , "Pacific islands region" , "remote area" , "Islands of the south Pacific -- a neo-CIA (anag)" .)