Office sweetheart seen around outskirts of Uttoxeter (6)
I believe the answer is:
bureau
'office' is the definition.
('bureau' can be a synonym of 'office')
'sweetheart seen around outskirts of uttoxeter' is the wordplay.
'sweetheart' becomes 'beau' (I've seen this before).
'seen around' is an insertion indicator.
'outskirts of' means to remove the middle letters.
'uttoxeter' with its middle removed is 'ur'.
'beau' going around 'ur' is 'BUREAU'.
(Other definitions for bureau that I've seen before include "The ------, familiar name of the FBI" , "Agency - writing desk" , "Writing desk with drawers" , "Item of furniture" , "Piece of furniture with drawers" .)