On ecstasy men take first the Spanish ingredient (7)
I believe the answer is:
element
'ingredient' is the definition.
(I know that ingredient can be written as element)
'on ecstasy men take first the spanish' is the wordplay.
'on' says to put letters next to each other.
'ecstasy' becomes 'E' (informal term for the drug).
'take first' becomes 't' (1st letter of 'take').
'the spanish' becomes 'el' ('the' in Spanish).
'e'+'men'+'t'='ement'
'ement' put after 'el' is 'ELEMENT'.
(Other definitions for element that I've seen before include "part of cooker" , "that's used in heating" , "Earth, water, air or fire" , "Basic constituent part" , "Wire in electric fire" .)