On filling initial curriculum vitae, set out to be original (8)
I believe the answer is:
creative
'be original' is the definition.
(associated in meaning)
'on filling initial curriculum vitae set out' is the wordplay.
'on' becomes 're' ('on' can be mean 'with reference to').
'filling' is an insertion indicator.
'initial' says to take the initial letters.
'set out' indicates an anagram.
The initial letter of 'curriculum' is 'c'.
'c'+'vitae'='cvitae'
'cvitae' anagrammed gives 'cative'.
're' going into 'cative' is 'CREATIVE'.
'to' acts as a link.
(Other definitions for creative that I've seen before include "Using the imagination" , "Showing imagination" , "Artistically inventive" , "Reactive in artistic manner" , "Imaginative, inventive" .)