On watch in rough Soho district (9)
I believe the answer is:
chinatown
'soho district' is the definition.
The definition suggests a singular noun which matches the answer.
'on watch in rough' is the wordplay.
'rough' indicates an anagram (a rough or broken ordering of the letters).
'on'+'watch'+'in'='onwatchin'
'onwatchin' with letters rearranged gives 'CHINATOWN'.
Can you help me to learn more?
(Other definitions for chinatown that I've seen before include "London area north of Leicester Square" , "Ethnic city quarter" , "area dominated by Asian influences" , "Oriental area of a city" , "where Asians live" .)