Once again, newly (6)
I believe the answer is:
afresh
I believe this clue is a double definition.
'once again' is the first definition.
(I've seen this before)
'newly' is the second definition.
(synonyms)
(Other definitions for afresh that I've seen before include "Anew, from the beginning" , "Newly" , "In a new way" , "In a different way" , "Academy award" .)