Once more arrange holiday destination (6)
I believe the answer is:
resort
'holiday destination' is the definition.
(I've seen this before)
'once more arrange' is the wordplay.
'once more' becomes 're' (I've seen this in other clues).
'arrange' becomes 'sort' (I've seen this before**).
're'+'sort'='RESORT'
(Other definitions for resort that I've seen before include "Scarborough?" , "Here we play" , "Watering-place" , "Where one may stay in hotel" , "Put fresh order" .)