One abandoned actors with a Method (8)
I believe the answer is:
castaway
'one abandoned' is the definition.
(thesaurus)
'actors with a method' is the wordplay.
'actors' becomes 'cast' (I've seen this before).
'with' is a charade indicator (letters next to each other).
'method' becomes 'way' (I've seen this before).
'cast'+'a'+'way'='CASTAWAY'
(Other definitions for castaway that I've seen before include "just one left on the Strand?" , "Desert island resident" , "Shipwrecked character" , "One marooned on remote island" , "Shipwreck survivor" .)