One beats up lecturer during drunken spree (7)
I believe the answer is:
blender
'one beats up' is the definition.
(appliance which beats up or smashes food)
'lecturer during drunken spree' is the wordplay.
'lecturer' becomes 'l'.
'during' is an insertion indicator.
'drunken spree' becomes 'bender' (I've seen this before).
'l' inserted within 'bender' is 'BLENDER'.
(Other definitions for blender that I've seen before include "kitchen equipment" , "(Food) mixer" , "Kitchen appliance" , "Kitchen liquidiser" , "used to make assets liquid?" .)