One business area's last resort (5)
I believe the answer is:
ibiza
'resort' is the definition.
(I've seen this before)
'one business area's last' is the wordplay.
'one' becomes 'I' (Roman numeral).
'business' becomes 'biz' (biz is a kind of business).
'last' says to take the final letters.
The final letter of 'area' is 'a'.
'i'+'biz'+'a'='IBIZA'
(Other definitions for ibiza that I've seen before include "Mediterranean location" , "holiday destination" , "Clubbers' island" , "One of the Balearic Islands" , "holiday resort" .)