One can get under-adjusted, of course (6)

I believe the answer is:
inured
'adjusted of course' is the definition.
'inured' can be an answer for 'adjusted' (thesaurus). I'm not certain of the 'of course' bit.
I don't understand the remainder of the clue.
Can you help me to learn more?
(Other definitions for inured that I've seen before include "Hardened against, emotion say" , "Accustomed to hardship" , "Hardened, accustomed" , "Hardened, maybe ruined" , "Toughened through exposure" .)
