One daughter in French region making fortune (10)
I believe the answer is:
providence
'fortune' is the definition.
(providence is a kind of fortune)
'one daughter in french region' is the wordplay.
'one' becomes 'i' (Roman numeral).
'daughter' becomes 'd'.
'in' means one lot of letters goes inside another.
'french region' becomes 'provence' (I've seen this before).
'i'+'d'='id'
'id' placed into 'provence' is 'PROVIDENCE'.
'making' is the link.
(Other definitions for providence that I've seen before include "US state capital" , "tender care" , "fortune" .)