One is upset making din (5)
I believe the answer is:
noise
'din' is the definition.
(I've seen this before)
'one is upset' is the wordplay.
'upset' indicates anagramming the letters.
'one'+'is'='oneis'
'oneis' is an anagram of 'NOISE'.
'making' acts as a link.
(Other definitions for noise that I've seen before include "Unpleasant sounds" , "Racket, din" , "Hubbub" , "Unwanted sound" , "Fuss" .)