One not given to travel (4-2-4)
I believe the answer is:
stay-at-home
'one not given to travel' is the definition.
(I've seen this before)
This is all the clue.
(Other definitions for stay-at-home that I've seen before include "One not given to travel" , "Person disinclined to travel" , "Unadventurous in travel" , "Don't go out" .)