One over with a North American (5)
I believe the answer is:
iowan
'north american' is the definition.
'iowan' can be an answer for 'american' (someone from Iowa). I'm not sure about the 'north' bit.
'one over with a' is the wordplay.
'one' becomes 'i' (Roman numeral).
'over' becomes 'o' (cricket abbreviation).
'with' becomes 'w' (abbreviation).
'a' becomes 'an'.
'i'+'o'+'w'+'an'='IOWAN'
(Other definitions for iowan that I've seen before include "Midwesterner" , "From Des Moines, say?" , "US resident" , "One from Des Moines perhaps" , "Statesman" .)