One skins up to get unconscious (6)
I believe the answer is:
asleep
'unconscious' is the definition.
('asleep' can be similar in meaning to 'unconscious')
'one skins up to' is the wordplay.
'one skins' means to remove the middle letters (I've seen 'skin' mean this).
'up' becomes 'amiss' (I've seen this before).
'to' becomes 'leep' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'amiss' with its centre taken out is 'as'.
'as'+'leep'='ASLEEP'
'get' is the link.
Can you help me to learn more?
(Other definitions for asleep that I've seen before include "Conked out" , "In the Land of Nod" , "not paying attention" , "like a kipper" , "In slumber" .)