One traipsed around in misery (11)
I believe the answer is:
desperation
'misery' is the definition.
(thesaurus)
'one traipsed around' is the wordplay.
'around' indicates anagramming the letters.
'one'+'traipsed'='onetraipsed'
'onetraipsed' is an anagram of 'DESPERATION'.
'in' is the link.
(Other definitions for desperation that I've seen before include "Complete lack of hope" , "State of despair" , "State of hopelessness" , "'Torment'" , "A state without hope" .)