One wound up in US resort (5)
I believe the answer is:
miami
'us resort' is the definition.
(resort in Florida)
'one wound up' is the wordplay.
'one' becomes 'i' (Roman numeral).
'wound' becomes 'maim' (I've seen this before).
'up' says the letters should be written in reverse (in down clue: letters go upwards).
'i'+'maim'='imaim'
'imaim' back-to-front is 'MIAMI'.
'in' is the link.
(Other definitions for miami that I've seen before include "Prejudice in favour of one person or thing" , "US city" , "I put out of action when returning" , "Popular sun-city of Florida" , "Port in Florida" .)