One's confused, giving negative responses (4)
I believe the answer is:
noes
'negative responses' is the definition.
(I've seen this before)
'one's confused' is the wordplay.
'confused' indicates an anagram.
'ones' is an anagram of 'NOES'.
'giving' is the link.
(Other definitions for noes that I've seen before include "Those disagreeing" , "Negative voters'" , "they are dissenting" , "Opponents" , "denials" .)