Only Noel can make it (4)
I believe the answer is:
lone
'only' is the definition.
(synonyms)
'noel can make it' is the wordplay.
'noel' can be anagrammed to 'LONE'.
However, I am not sure how the anagram is indicated.
Can you help me to learn more?
(Other definitions for lone that I've seen before include "Sole" , "Solitary or single" , "Companionless" , "Unaccompanied" , "He likes to operate by himself" .)