Onset of enmity has you, red-hot, turning up making wicked stare (4,3)
I believe the answer is:
evil eye
'wicked stare' is the definition.
(a malicious glare)
'onset of enmity has you red-hot turning up' is the wordplay.
'onset of' indicates taking the first letters.
'has' is a charade indicator (letters next to each other).
'you' becomes 'ye' (historical version of 'you').
'red-hot' becomes 'live' (both can mean exciting or topical).
'turning up' says the letters should be written backwards.
The first letter of 'enmity' is 'e'.
'e'+'ye'+'live'='eyelive'
'eyelive' in reverse letter order is 'EVIL EYE'.
'making' is the link.
(Other definitions for evil eye that I've seen before include "Nasty look" , "Bad-luck look" , "Look superstitiously believed to cause harm" , "Supposedly harmful glance" , "Supposedly harmful stare" .)