Opened grasping instrument - neat! (9)
I believe the answer is:
undiluted
'neat' is the definition.
('undiluted' can be similar in meaning to 'neat')
'opened grasping instrument' is the wordplay.
'opened' becomes 'undid' (I can't justify this - if you can you should give a lot more credence to this answer).
'grasping' means one lot of letters goes inside another.
'instrument' becomes 'lute' (lute is a kind of instrument).
'undid' going around 'lute' is 'UNDILUTED'.
Can you help me to learn more?
(Other definitions for undiluted that I've seen before include "At original strength" , "Neat" .)