Openers in Derbyshire's innings set county record (4)
I believe the answer is:
disc
'record' is the definition.
(eg a CD, compact disc)
'openers in derbyshire's innings set county' is the wordplay.
'openers in' suggests taking the first letters (the letters which open the words).
The initial letters of 'derbyshire innings set county' is 'DISC'.
(Other definitions for disc that I've seen before include "Gramophone record" , "Protein-constituent acid" , "Thin flat circular object" , "something moving in the spine" , "Sound recording" .)