Opening of hotel in French resort (5)
I believe the answer is:
niche
'opening' is the definition.
'hotel in french resort' is the wordplay.
'hotel' becomes 'h' (phonetic alphabet: alpha, bravo, charlie etc.).
'in' indicates putting letters inside.
'french resort' becomes 'nice' (French coastal resort).
'h' inserted into 'nice' is 'NICHE'.
'of' is the link.
(Other definitions for niche that I've seen before include "Suitable location" , "Nook, cranny" , "Chine (anag) - suitable place in life" , "Small corner of e.g. market" , "A small recess or easy job" .)