Operation by hospital in attempt for prize (6)
I believe the answer is:
trophy
'for prize' is the definition.
(synonyms)
'operation by hospital in attempt' is the wordplay.
'operation' becomes 'op'.
'by' is a charade indicator (letters next to each other).
'hospital' becomes 'H' (abbreviation for hospital on maps).
'in' is an insertion indicator.
'attempt' becomes 'try' (synonyms).
'op'+'h'='oph'
'oph' going inside 'try' is 'TROPHY'.
(Other definitions for trophy that I've seen before include "Memorial of victory" , "Prize or token of victory" , "Laurels" , "leading award" , "Victor's prize" .)