Order wretched individual to leave home (4)
I believe the answer is:
sect
'order' is the definition.
(I've seen this in other clues)
'wretched individual to leave home' is the wordplay.
'wretched individual' becomes 'insect' (insect can mean a wretched person).
'to leave' indicates named letters should be taken away.
'home' becomes 'in' ('he's home' can mean 'he's in').
'insect' with 'in' taken out is 'SECT'.
(Other definitions for sect that I've seen before include "Subdivision of a larger religious group" , "Denomination" , "Small group with own religious beliefs" , "Subdivision of a religion" , "Religious splinter group" .)