Oscar inside of machine cannot stand (6)
I believe the answer is:
loathe
'cannot stand' is the definition.
(I've seen this before)
'oscar inside of machine' is the wordplay.
'oscar' becomes 'Wilde' (playwright Oscar Wilde).
'inside' means to look at the middle letters.
'of' becomes 'o''.
'machine' becomes 'athe' (I can't explain this - if you can you should believe this answer much more).
The centre of 'wilde' is 'l'.
'l'+'o'+'athe'='LOATHE'
Can you help me to learn more?
(Other definitions for loathe that I've seen before include "Can't abide" , "Can't stand" , "Abhor, abominate" , "Abhor, execrate" , "Strongly detest" .)