Out of control in the main (6)
I believe the answer is:
adrift
'out' is the definition.
(thesaurus)
I cannot understand how the remainder of the clue works.
Can you help me to learn more?
(Other definitions for adrift that I've seen before include "Floating uncontrolled" , "Not anchored, floating freely" , "Wandering aimlessly" , "Afloat without steerage" , "cut loose" .)