Outcast, pariah (5)
I believe the answer is:
leper
This clue is a double definition.
'outcast' is the first definition.
(I know that leper is a type of outcast)
'pariah' is the second definition.
(I know that leper is a type of pariah)
(Other definitions for leper that I've seen before include "He's avoided" , "sick person" , "Social outcast" , "Social reject" , "Sufferer from dread disease, once made to wear bell" .)