Outsize nurse in port (6)
I believe the answer is:
ostend
'port' is the definition.
(I've seen this before)
'outsize nurse' is the wordplay.
'outsize' becomes 'os'.
'nurse' becomes 'tend' (I've seen this before).
'os'+'tend'='OSTEND'
'in' is the link.
(Other definitions for ostend that I've seen before include "Port -- stoned (anag)" , "Port - doesn't (anag)" , "European port" , "cross-channel port" , "Belgian port and resort" .)