Over-refined (6)
I believe the answer is:
effete
'over-refined' is the definition.
(I've seen this before)
This is the entire clue.
(Other definitions for effete that I've seen before include "Lacking in power" , "Over-refined, exhausted" , "Feeble, having lost vitatlity" , "Enfeebled" , "Decadent - worn out" .)