Overturning some in-house policies takes great strides (5)
I believe the answer is:
lopes
'great strides' is the definition.
'overturning some in-house policies' is the wordplay.
'overturning' is a reversal indicator.
'some in' indicates the answer is hidden within the clue.
'sepol' can be found hidden inside 'house policies'.
'sepol' backwards is 'LOPES'.
'takes' is the link.
(Other definitions for lopes that I've seen before include "Bounds" , "Runs with long bounding steps" , "Runs using poles" , "Runs easily" .)