'Paddington's Home' screened by picture palace from the East End (4)
I believe the answer is:
peru
'paddington's home' is the definition.
(home of the fictional bear)
'screened by picture palace from the east end' is the wordplay.
'screened by' says the answer is hidden in the clue.
'from the east end' is a reversal indicator (from east to west).
'urep' can be found hidden inside 'picture palace'.
'urep' written backwards gives 'PERU'.
(Other definitions for peru that I've seen before include "Land of the Incas" , "Andes republic" , "Homeland of Paddington Bear" , "Machu Picchu country" , "Nazca, Cuzco here" .)