Painting by Leonardo (4,4)

I believe the answer is:

mona lisa

(Other definitions for mona lisa that I've seen before include "Mysterious-smile Louvre portrait" , "Famous painting of enigmatic woman by de Vinci" , "depicted, in the Louvre" , "Fertiliser from seabirds" , "Da Vinci painting" .)

I've seen this clue in The Times.

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