Pair seen with one boy can (6)
I believe the answer is:
prison
'can' is the definition.
(The Can is slang for prison)
'pair seen with one boy' is the wordplay.
'pair' becomes 'pr' (abbreviation).
'seen with' means one lot of letters go next to another.
'one' becomes 'I' (Roman numeral).
'boy' becomes 'son' (synonyms).
'pr'+'i'+'son'='PRISON'
(Other definitions for prison that I've seen before include "cage" , "Place of incarceration" , "Gaol" , "Wormwood Scrubs, for example" , "porridge" .)