Crossword Genius

Pandora releases (4)

Ross

I believe the answer is:

ills

(Other definitions for ills that I've seen before include "Sicknesses or misfortunes" , "God-like" , "Ailments, misfortunes" , "Sicknesses or harms" , "Evils or sicknesses" .)

I've seen this clue in The New York Times.
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