Parents manage to crush one's spirit (7,4)
I believe the answer is:
mothers ruin
'spirit' is the definition.
('mother's ruin' is a name for gin)
'parents manage to crush one's' is the wordplay.
'parents' becomes 'mothers' (mother is a kind of parent).
'manage' becomes 'run' (both can mean to organise).
'to crush' is an insertion indicator (inserted letters are crushed between others).
'one' becomes 'i' (Roman numeral).
'run' enclosing 'i' is 'ruin'.
'mothers'+'ruin'='MOTHERS RUIN'
(Other definitions for mothers ruin that I've seen before include "Gin (in popular parlance)" , "Gordon's" .)