Pariah not at home with actors (7)
I believe the answer is:
'pariah' is the definition.
(I know that pariah can be written as outcast)
'not at home with actors' is the wordplay.
'not at home' becomes 'out' (out can mean away from home).
'with' says to put letters next to each other.
'actors' becomes 'cast' (group of actors).
(Other definitions for outcast that I've seen before include "untouchable" , "Role of Ishmael" , "Rejected individual" , "'Person excluded from society, a pariah (7)'" , "one sent to Coventry" .)