Part of a shoe disturbed lesion (6)
I believe the answer is:
insole
'part of a shoe' is the definition.
('insole' is part of 'shoe')
'disturbed lesion' is the wordplay.
'disturbed' is an anagram indicator.
'lesion' with letters rearranged gives 'INSOLE'.
(Other definitions for insole that I've seen before include "found in boot" , "Inner part of shoe" , "Boots may be holding it" , "Lesion in part of foot" , "Padding in a shoe" .)