Part of hotel seems different (4)
I believe the answer is:
else
'different' is the definition.
('else' can be a synonym of 'different')
'part of hotel seems' is the wordplay.
'part of' says the answer is hidden in the clue.
'ELSE' is hidden in the letters of 'hotel seems'.
(Other definitions for else that I've seen before include "Alternatively" , "As an alternative" , "Otherwise; different from" , "In addition, besides" , "Other than (what is under consideration)" .)