Pay up front with a loan from Mum and Dad? (8)
I believe the answer is:
parental
'from mum and dad?' is the definition.
(from your parents)
'pay up front with a loan' is the wordplay.
'up front' says to take the initial letters (the letter at the front of the word).
'with' is a charade indicator (letters next to each other).
'loan' becomes 'rental' (rental can mean something loaned).
The first letter of 'pay' is 'p'.
'p'+'a'+'rental'='PARENTAL'
(Other definitions for parental that I've seen before include "Of mother and/or father" , "Relating to mother and father" , "of old man and woman" , "like mum and dad" , "of father, perhaps" .)