Penelope's lost one by silly sly uses (7)
I believe the answer is:
ulysses
'penelope's lost one' is the definition.
I can't judge whether this defines the answer.
'silly sly uses' is the wordplay.
'silly' indicates anagramming the letters.
'sly'+'uses'='slyuses'
'slyuses' is an anagram of 'ULYSSES'.
'by' acts as a link.
Can you help me to learn more?
(Other definitions for ulysses that I've seen before include "Wandering Greek hero or novel by James Joyce" , "name given to US President at birth" , "Old seafarer" , "Famous novel by James Joyce" , "name for Civil War hero" .)