Perforate, prick (6)
I believe the answer is:
pierce
I believe this is a double definition.
'perforate' is the first definition.
(I know that perforate is a more specific form of pierce)
'prick' is the second definition.
(I know that prick is a more specific form of pierce)
(Other definitions for pierce that I've seen before include "Make hole in with something sharp" , "Stick a pin in" , "Possibly drill" , "- Brosnan; (to) hole" , "Make hole in with sharp object" .)