Period with first of Georges in control? (5)
I believe the answer is:
reign
'period' is the definition.
(I know that reign is a type of time period)
'first of georges in control?' is the wordplay.
'first of georges' becomes 'g' (rst letter of 'georges').
'in' indicates putting letters inside.
'control?' becomes 'rein' (reining is a kind of controlling).
'g' placed inside 'rein' is 'REIGN'.
'with' acts as a link.
(Other definitions for reign that I've seen before include "Have sovereign power" , "Period of monarch" , "Sit on a throne" , "Spell in office" , "Monarch's period" .)