Perk up and ask about Argo's trip (10)
I believe the answer is:
invigorate
'perk up' is the definition.
(invigorating is a kind of perking up)
'ask about argo's trip' is the wordplay.
'ask' becomes 'invite' (inviting is a kind of asking).
'about' means one lot of letters goes inside another.
'trip' indicates anagramming the letters.
'argo' with letters rearranged gives 'gora'.
'invite' enclosing 'gora' is 'INVIGORATE'.
'and' acts as a link.
(Other definitions for invigorate that I've seen before include "Give energy to" , "Perk up" , "Liven up" , "Give strength to" , "Strengthen" .)